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Adenosine 3',5'-Cyclic Monophosphate
Catalog NO.: CMP-001 | CAS NO.: 60-92-4 | Brand: BIOCAXIS
Category
Nucleosides & Nucleotides, Nucleotide
Synonyms:
Cyclic AMP; cAMP; Adenosine 3',5'-cyclophosphate;
4H-Furo[3,2-d]-1,3,2-dioxaphosphorin-7-ol, 6-(6-amino-9H-purin-9-yl)tetrahydro-2-hydroxy-, 2-oxide, (4aR,6R,7R,7aS)-; cyclic
Adenosine 3',5'-monophosphate
Molecular Formula
C10H12N5O6P
Molecular Weight
329.21
General description
Adenosine 3′,5′-cyclic monophosphate has been
used:
as cell culture medium supplement in embryonic spinal
neurons
as a component of ringer solution
for perfusion studies
to induce neuroendocrine differentiation in human lung
cancer cell lines
Biochem/physiol Actions
Naturally-occurring
activator of cyclic-AMP-dependent protein kinase (PKA). The cAMP/PKA signaling
pathway inhibits cell proliferation, induces differentiation and leads to
apoptosis.
Naturally-occurring
activator of cyclic-AMP-dependent protein kinase (PKA). cAMP
is an important second messenger that is linked in many systems to
neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA
signaling pathway has been shown to inhibit cell proliferation, induce
differentiation and lead to apoptosis.