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Guanosine 5′-diphosphate
Catalog NO.: NDP-003 | CAS NO.: 146-91-8 | Brand: BIOCAXIS
Category
Nucleosides & Nucleotides, Nucleotide
Synonyms:
5′-GDP;
Guanosine diphosphate; GDP
Molecular Formula
C10H15N5O11P2
Molecular Weight
443.20
General description
Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate
that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine
5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6
(IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation
(AI).
At equivalent molar concentrations, both the salt and free
forms of a compound exhibit comparable biological activity. Nevertheless, the
salt form (Guanosine 5'-diphosphate disodium salt) usually boasts enhanced
water solubility and stability.