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DMT-2'-Fluoro-dA(Bz) Phosphoramidite

Catalog NO.: RNA-FPM-001 | CAS NO.: 136834-22-5 | Brand: BIOCAXIS

Category

Carbohydrates, Nucleosides & Nucleotides, RNA Phosphoramidites

Synonyms:

N-Benzoyl-5'-O-(4,4'-Dimethoxytrityl)-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-2'-fluoroadenosine N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-2'-fluoroadenosine

Molecular Formula

C₄₇H₅₁FN₇O₇P

Molecular Weight

875.94

General description

Dmt-2'fluoro-da(bz) amidite, an uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotide, is a nuclease-resistant antisense compound with high affinity and specificity for RNA targets. Dmt-2'fluoro-da(bz) amidite is also an intermediate for 5’-DMT-3’-phosphoramidite synthesis.

Usage

Solid phase synthesis of DNA and RNA oligonucleotides in chemical or enzymatic processes.

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